API reference
SELEGILINE HCl
- CAS number
- 14611-52-0
- Molecular formula
- C13H18ClN
- Molecular weight
- 223.74 g/mol
About this molecule
Selegiline Hydrochloride is the hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkinsonian effect. As a selective monoamine oxidase (MAO) inhibitor, selegiline has the greatest affinity for type B MAO, found mainly in the brain. Selegiline is converted by MAO B to an active moiety, which binds irreversibly at the active site of the enzyme's cofactor FAD (flavin adenine dinucleotide) molecule. This prevents the oxidative deamination of catecholamines and serotonin by MAO B, and leads to an increase in these neurotransmitters' activities resulting in improved motor function. In addition, this agent may inhibit re-uptake of dopamine by the neuron and prolong dopamine activity.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride
- InChIKey
- IYETZZCWLLUHIJ-UTONKHPSSA-N
- SMILES
- C[C@H](CC1=CC=CC=C1)N(C)CC#C.Cl
- PubChem CID
- 26758
Also known as
Selegiline hydrochloride · Selegiline Hcl · l-Deprenyl hydrochloride · (-)-Deprenyl hydrochloride · Jumex hydrochloride · Eldepryl hydrochloride · Ensam · (-)-Deprenil hydrochloride
Related entries in the range
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