API reference
ZIPRASIDONE HCl
- CAS number
- 122883-93-6
- Molecular formula
- C21H22Cl2N4OS
- Molecular weight
- 449.4 g/mol
About this molecule
Ziprasidone Hydrochloride is the hydrochloride salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone hydrochloride functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone hydrochloride also inhibits synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone hydrochloride exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrochloride
- InChIKey
- NZDBKBRIBJLNNT-UHFFFAOYSA-N
- SMILES
- C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.Cl
- PubChem CID
- 219099
Also known as
Ziprasidone hydrochloride · Ziprasidone HCl · Zeldox · ziprasidone hydrochloride, monohydrate · Geodon, Capsules · CP-88,059-1 · Geodon · Ziprasidone (hydrochloride)
Related entries in the range
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