API reference
Ziprasidone mesilate trihydrate
- CAS number
- 199191-69-0
- Molecular formula
- C22H31ClN4O7S2
- Molecular weight
- 563.1 g/mol

About this molecule
Ziprasidone Mesylate is the mesylate salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone mesylate functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone mesylate also inhibits the synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone mesylate exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.
Source: NCI Thesaurus (NCIt), via PubChem.
Identifiers
- IUPAC name
- 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;methanesulfonic acid;trihydrate
- InChIKey
- WLQZEFFFIUHSJB-UHFFFAOYSA-N
- SMILES
- CS(=O)(=O)O.C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.O.O
- PubChem CID
- 656685
Also known as
Ziprasidone mesylate · Ziprasidone mesylate trihydrate · Ziprasidone mesylate hydrate · Ziprasidone mesilate trihydrate · CP-88, 059-27 · ZIPRASIDONE MESILATE (MART.) · ZIPRASIDONE MESILATE TRIHYDRATE (EP MONOGRAPH) · Geodon, for Injection
Related entries in the range
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