Echothiophate Iodide

Indications

INDICATIONS AND USAGE Reduction of Elevated IOP Echothiophate iodide for ophthalmic solution is indicated for the reduction of elevated IOP. Accommodative Esotropia Concomitant esotropias with a significant accommodative component.

Dosage and administration (summary)

DOSAGE AND ADMINISTRATION

Contraindications

CONTRAINDICATIONS Active uveal inflammation. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block. Hypersensitivity to the active or inactive ingredients.

Warnings and precautions

WARNINGS Succinylcholine should be administered only with great caution, if at all, prior to or during general anesthesia to patients receiving anticholinesterase medication because of possible respiratory or cardiovascular collapse. Caution should be observed in treating elevated IOP with echothiophate iodide for ophthalmic solution in patients who are at the same time undergoing treatment with systemic anticholinesterase medications, because of possible adverse additive effects.

Pregnancy

Pregnancy Teratogenic Effects Animal reproduction studies have not been conducted with echothiophate iodide for ophthalmic solution. It is also not known whether echothiophate iodide for ophthalmic solution can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

Storage and supply

HOW SUPPLIED Each package contains sterile echothiophate iodide for ophthalmic solution, sterile diluent, and dropper for dispensing 5 mL eyedrops. NDC 48102-053-05 ................... 6.25 mg package for 0.125% White amorphous deposit on bottle walls. Aluminum crimp seal is green.

Source: Echothiophate Iodide For Ophthalmic Solution (Phospholine Iodide) — US FDA prescribing information, 2025-07-07, DailyMed. Summarised and shortened; the full label governs. Iranian registration, indications and labelling may differ.